Prolonged Course Of Antimicrobial Therapy
Prolonged course of antimicrobial therapy (PCAT) refers to taking antibiotics, antifungals, antivirals, or other antimicrobial agents for a longer period of time than what is typically prescribed for an infection. This kind of therapy is also known as long-term antibiotic therapy (LTAT). It is sometimes used for chronic infections which cannot be cured with a standard course of treatment, such as Lyme disease, chronic sinusitis, or certain skin infections. In some cases, PCAT is given to keep an infection under control even when the chances of a full cure are minimal. It is sometimes used in cases where a single short course of antibiotics fails to effectively treat an infection or when existing infection-fighting medicines become ineffective. At times, PCAT may be necessary to prevent a secondary infection or to deal with underlying health conditions that put the patient at greater risk of infection, such as a compromised immune system due to chemotherapy or HIV/AIDS. PCAT requires close monitoring since there is a heightened risk of side effects, particularly when used for long periods of time. The risk of antimicrobial resistance is also an issue that must be taken into consideration. As such, PCAT is typically only recommended in certain cases after careful evaluation. Patients at greatest risk for serious infections should also be closely monitored for potential complications when taking antimicrobials for an extended period of time.
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DURATION OF ANTIBIOTIC THERAPY FOR COMMON INFECTIONS
Web Apr 29, 2021 Short courses of therapy (3–5 d, depending on antibiotic class) for uncomplicated cystitis in otherwise healthy young women is well-supported by robust … ...
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Author Jennifer Grant, Nicole Le SauxPublish Year 2021
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SAFETY OF PROLONGED OUTPATIENT COURSES OF INTRAVENOUS …
Web Jan 7, 2022 The perceived need for prolonged intravenous antibiotic courses has become a major driver behind the growth of outpatient parenteral antimicrobial therapy (OPAT) services. Several recent … ...
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Get CodeLIFE-LONG ANTIMICROBIAL THERAPY: WHERE IS THE EVIDENCE?
Web Oct 1, 2018 Prolonged courses of antibiotics have been used for prophylaxis and suppression of infection since 1962 when penicillins were first used in managing sickle … ...
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Author Jillian Shu Yun Lau, Tony M. Korman, Ian WoolleyEstimated Reading Time 9 minsPublish Year 2018
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Web Sep 27, 2020 A retrospective cohort study conducted by Nelson et al concluded that long-course antibiotic treatment may be superior to short-course. 11 Two recently … ...
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Author Xiaoming Li, Chao Liu, Zhi Mao, Qinglin Li, Shuang Qi, Feihu ZhouPublish Year 2021
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Web Mar 27, 2021 In summary, short-course antibiotic therapy for low-risk MS-SAB yielded similar outcomes as prolonged courses in terms of both mortality and relapse. The … ...
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SHORT‐COURSE VERSUS PROLONGED‐COURSE ANTIBIOTIC THERAPY …
Web Aug 24, 2015 We considered all randomised controlled trials (RCTs) comparing a fixed 'short' duration of antibiotic therapy with a 'prolonged' course for HAP (including … ...
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Web Oct 4, 2021 Short-course antimicrobial therapy may be as effective as prolonged-course therapy for the treatment of patients with uncomplicated bloodstream infections … ...
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Web Abstract Background: Guidelines recommend an antimicrobial therapy duration of four to seven days for intra-abdominal infections (IAIs). Despite evidence that shorter treatments … ...
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Web Aug 24, 2015 Objectives: To assess the effectiveness of short versus prolonged-course antibiotics for HAP in critically ill adults, including patients with VAP. Search methods: ...
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SHORT VERSUS PROLONGED COURSES OF ANTIMICROBIAL THERAPY FOR …
Web Sep 30, 2021 The prolonged-course therapy did not significantly reduce the risk of the recurrence of P. aeruginosa infection within 180 days compared with short-course … ...
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Web Short- versus prolonged-course antibiotic therapy for sepsis or infectious diseases in critically ill adults: a systematic review and meta-analysis Kenji Kubo , Yutaka Kondo , … ...
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Web Jan 17, 2022 We thank Hagiya and Otsuka 1 for their interest in our study on a short course of antimicrobial therapy in uncomplicated Pseudomonas aeruginosa … ...
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Web Dec 4, 2021 All patients with uncomplicated P. aeruginosa BSI admitted at a tertiary-care hospital from May 2016 to September 2020 were included. We compared the rate of … ...
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SHORT VERSUS PROLONGED COURSES OF ANTIBIOTIC THERAPY FOR CHILDREN …
Web Oct 24, 2013 Antibiotic treatment for more than 10 days for uncomplicated bacteraemia in children does not reduce the risk of microbiological relapse compared with shorter … ...
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Web Dec 24, 2021 Abstract Background: The optimal duration of antimicrobial therapy for uncomplicated Pseudomonas aeruginosa bloodstream infection (BSI) is unknown. We … ...
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Web Jan 31, 2019 The management of complex orthopedic infections usually includes a prolonged course of intravenous antibiotic agents. We investigated whether oral … ...
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Web Jul 24, 2017 Infections can be difficult to treat and require prolonged antibiotic courses. Unless surgical intervention is undertaken to remove debris and/ or drain abscesses, … ...
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EVALUATING ANTIMICROBIAL DURATION FOR GRAM‐NEGATIVE BACTEREMIA IN ...
Web Jun 6, 2023 Background. In the management of Gram-negative bloodstream infection (GN-BSI), short antimicrobial courses have been increasingly demonstrated to be non … ...
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Web The case for shortening antimicrobial duration of therapy in selected infections Although antibiotics are commonly viewed as “safe” medications, the potential advantages of … ...
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Web May 3, 2023 Most patients who plan to receive prolonged parenteral antimicrobial therapy as outpatients have received the first dose as an inpatient and demonstrated … ...
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Web The median duration of therapy in the short and prolonged courses was 10 days (IQR 10-10) and 14 days (IQR 14-17), respectively. The 30 day mortality was similar between the … ...
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SHORT-COURSE VERSUS PROLONGED-COURSE ANTIBIOTIC THERAPY FOR …
Web Aug 24, 2015 The relative merits of fixed short versus prolonged‐course antibiotic therapy have been under‐explored, and the optimal duration of therapy for patients with NF‐GNB … ...
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Web The optimal duration of antimicrobial treatment for ventilator-associated pneumonia (VAP) is unknown, however, there is a growing evidence that reduction in the length of … ...
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Web Jun 5, 2023 AIM: To investigate if shorter-course antibiotic treatments could be similarly effective to long-course treatments in adults with AC. METHODS: This study constitutes … ...
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Web Sep 30, 2021 Conclusions Short-course antimicrobial therapy could be as effective as prolonged-course therapy for uncomplicated P. aeruginosa BSI. Discover the world's … ...
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